RNA vaccines are just the tip of the iceberg. Ruby Jackson discusses how this versatile molecule is revolutionising medicine ...

An accidental discovery turned into an unexpected success when a team of interdisciplinary BU researchers created a new and ...

mRNA vaccines and therapeutics are rapidly growing, driven by the success of COVID-19 vaccines. The 5’ cap structure is crucial for mRNA stability and expression. However, in-vitro transcribed mRNA ...

Research from the drug company Moderna suggests its new mpox vaccine, based on mRNA technology, might be more effective than ...

Structural studies reveal the mechanism by which the mRNA nuclear export machinery engages with nascent transcripts through interaction with the cap binding complex.

Small interfering RNA (siRNA) drugs are a class of therapeutic agents that silence specific genes associated with inherited diseases. However, siRNA drugs have challenges because siRNAs often silence ...

The end-to-end platform facilitates the study of therapeutic translation, stability-influencing structure, mRNA substance identity and integrity, and lipid nanoparticle and storage effects. In ...

An experimental Moderna mRNA vaccine for mpox has demonstrated greater effectiveness than current shots in reducing disease symptoms and duration, according to an animal study published in the ...

RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript ...

They decided to focus on modifying the chemical structure of a lesser-known type of RNA ... and at the same time the immune system is degrading it,” says Grinstaff. Standard mRNA COVID vaccines tell ...

Moderna's new candidate vaccine, called mRNA-1769, is targeted to only those bits of the mpox virus' structure that give recipients lasting, protective immune responses that ward off mpox ...