If not controlled, type 2 diabetes can cause serious complications such as vision problems (diabetic retinopathy), ...

Indeed, phenformin, an antidiabetic drug that belongs to the same class as metformin, was withdrawn from the market in 1977 because of the high incidence of lactic acidosis associated with its use.

Metformin has been used in the treatment of ... (which was removed from the market after several hundred cases of lactic acidosis were reported), numerous studies have since indicated that the ...

Certain medications and toxins can also lead to type B lactic acidosis. A prime example is a diabetes drug called metformin. Metformin works in the liver and gut to lower blood sugar levels, but it ...

In 1996, the Food and Drug Administration approved the labeling for metformin (dimethylbiguanide ... in 1977 because of an association with lactic acidosis. Buformin, another biguanide, is ...

If you've recently received a diagnosis of type 2 diabetes, understanding your treatment options is an important first step.

Metformin-associated lactic acidosis was associated with elevated blood lactate levels (>5 mmol/L), anion gap acidosis (without evidence of ketonuria or ketonemia), an increased lactate/pyruvate ...

One serious but rare side effect of metformin is lactic acidosis, says Dr. Jordan Messler, a hospitalist at Morton Plant Hospitalist group in Clearwater, Florida. Lactic acidosis occurs when ...

When prescribed appropriately, metformin causes few adverse effects—the most common is gastrointestinal upset—and is associated with a low risk of hypoglycemia. Lactic acidosis (a buildup of ...

Metformin HCl 500mg/5mL ... by increasing peripheral glucose uptake and utilization. Increased risk of lactic acidosis with topiramate, other carbonic anhydrase inhibitors (eg, zonisamide ...